Dr. Duman is Professor of Psychiatry and Neurobiology, Director of
the Abraham Ribicoff Research Facilities and the Jameson Professor of
Psychiatry at Yale. Studies from Dr. Duman’s laboratory have contributed to
characterization of the molecular and cellular actions of stress, depression,
and antidepressant treatments, providing the basis for a neurotrophic and
synaptic hypothesis of depression. He has also studied the role of the innate
immune system in the pathophysiology and treatment of depression. These findings
represent major advances in our understanding of the effects of antidepressants
and provide a framework for the development of novel therapeutic agents.
Duman has received several awards for his work, including the Anna-Monika
Prize, Nola Maddox Falcone Prize, Janssen Prize, NIMH MERIT Award and a NARSAD
Distinguished Investigator Award. He is author of over 300 original articles,
reviews and chapters and has given over 250 invited lectures.
Website: http://psychiatry.yale.edu/people/ronald_duman-1.profile
Ken
Mackie, M.D.
Linda
and Jack Gill Professor of Neuroscience
Department of Psychological and Brain Sciences
Indiana University Bloomington
Talk Title: "Cannabinoid receptor type 2 (CB2) signaling in neurons and the consequences of CB2 receptor functional selectivity"
Dr.
Mackie received his M.D. from Yale University, followed by postdoctoral studies
with Paul Greengard and Bertil Hille. He then completed his
anesthesiology residency at the University of Washington. While at the
University of Washington he began studying ion channel modulation by CB1
cannabinoid receptors, showing these receptors inhibit presynaptic calcium
channels and activate inwardly rectifying potassium channels. His lab
broadly studies cannabinoid biology, including pharmacology, signaling,
regulation, and distribution of cannabinoid receptors, developmental effects of
cannabinoids, and the interplay of endogenous and exogenous cannabinoids in synaptic
plasticity. In 2007 he moved to Indiana University where he is currently
a Linda and Jack Gill Professor of Neuroscience.
Website: http://psych.indiana.edu/faculty/kmackie.php
Mohammed Milad, Ph.D.
Professor of Psychiatry
Harvard University
Talk Title: "Fear extinction: 10 years of progress"
Dr. Milad is an Associate Professor
of Psychiatry at Harvard Medical School (HMS) and a Research Scientist at the
Department of Psychiatry at Massachusetts General Hospital (MGH). He serves as
the Director of the Behavioral Neuroscience Program within MGH where he conducts
translational research focused on examining the neural correlates of fear
extinction in rodents and humans using a multi-modal approach. Milad earned his
Ph.D. in Behavioral Neuroscience and his post-doctoral training at MGH and HMS.
He has received the Positive Neuroscience Award from the Templeton Foundation
and was named a Kavli Fellow by the National Academy of Sciences. He served as
an Institute of Medicine committee member, focusing on the improvement of
treatment and diagnosis for PTSD. Milad’s research has been supported by
NIMH, DOD and NARSAD.
Website: https://connects.catalyst.harvard.edu/profiles/display/person/14907
____________________________________________________________________________________________________________________________________________
CBBRe Speakers
Kathleen
Brown-Rice, Ph.D
Assistant Professor
Department of Counseling and Psychology
University of South Dakota
Talk Title: "Neural correlates of historical trauma among Native American adults"
Dr. Rice is an Assistant Professor at the University of South
Dakota. She received her Ph.D. in Counseling and Counselor Education from the
University of North Carolina Charlotte and is a Licensed Professional Counselor
(SD, NE, and NC), Licensed Mental Health Provider (NE), Certified Addiction
Counselor (SD), Licensed Clinical Addiction Counselor (LCAS), Approved Clinical
Supervisor and National Certified Counselor. Her research interests relate to
professional counselor supervision and training with a focus on ethical and
cross-cultural considerations, Native American mental health with an emphasis
on the implications of historical/generational trauma, risky substance use and
understanding emotional regulation through neural imaging. She has worked as a
professional counselor in various clinical mental health settings and continues
to practice part-time.
Taylor Bosch
Graduate Student
Ph.D. Program
Division of Basic Biomedical Sciences
Sanford School of Medicine
University of South Dakota
Talk Title: "Need a new vise? Alterations in neural activity following direct experience with unfamiliar tools"
Mr. Bosch is entering his third year of the Basic Biomedical
Sciences doctoral program with a specialization in neuroscience at the
University of South Dakota’s Sanford School of Medicine. He is an active member
of the Center for Brain and Behavior Research (CBBRe) and is slated to present
his research at the Society for Neuroscience annual conference. His research
interests include using cognitive techniques such as functional magnetic
resonance imaging (fMRI) and electroencephalography (EEG) to explain the
intricacies of the human motor system, with an emphasis on the neurological
correlates of tool use. Specifically, his research focuses on using action
observation to identify changes in neural activity that occur following the
acquisition of skilled tool use.
Indra Chandrasekar,
Ph.D.
Associate Scientist
Sanford Children’s Health Research Center
Sanford Research
Talk Title: "Role of nonmuscle myosin II in CNS synapses"
Dr. Chandrasekar obtained her master’s degree from Birla
Institute of Technology and Science, Pilani, India. Her passion for Cell
Biology took her to cytoskeletal research pioneer, Dr. Brigitte M. Jockusch’s
Lab in Germany, where she received training in basic cell biology concepts and
techniques. After receiving her Ph.D. (Dr.rer.nat) degree from Technical
University of Braunschweig in Germany, she moved to the U.S. Chandrasekar
performed a short postdoctoral fellowship in the laboratory of renowned actin
biologist, John Cooper, Ph.D. at Washington University School of Medicine in
St. Louis. After a baby break, she joined the lab of Paul Bridgman, Ph.D., an
expert cellular neurobiologist and EM specialist at Washington University,
where she received training in neuronal cytoskeleton, mouse models and advanced
microscopy techniques. She is currently an Associate Scientist in the
Children’s Health Research Center at Sanford Research. Her lab is interested in
the role of membrane trafficking pathways in cell and organ function.
Undergraduate Student
Department of Biology
College of Arts and Sciences
University of South Dakota
Talk Title: "Behavioral nuance in a novel animal model reveals a gradient of anxiety"
Melissa Prince has been an Undergraduate Research Assistant in
Cliff Summers’ lab for three years, with plans to enter into the USD Biology
Department doctoral program to obtain her Ph.D. in Neuroscience. As a member of
Summers’ lab, her research focuses on mechanisms that underlie decision making
in the context of social stress and anxiety. Using social defeat in a recently
developed model for mice, the Stress-Alternatives Model, her studies
investigate the role of amygdalar orexin as a modulator of anxiety and
depression. She is also a SPURA alumnus and mentor. She has presented her
research at the Society for Neuroscience’s annual conference, and is co-author
on a paper recently published in Physiology and Behavior.
Hongmin Wang, Ph.D.
Associate Professor
Basic Biomedical Sciences
Sanford School of Medicine
University of South Dakota
Talk Title: "Induced pluripotent stem cells in studies of Huntington’s disease"
Dr. Wang received his Ph.D. from the University of Idaho in
2000, and completed his postdoctoral training at the Johns Hopkins University
School of Medicine in Neurodegeneration. Wang is currently an Associate
Professor within the Division of Basic Biomedical Sciences at the Sanford
School of Medicine. His lab investigate the neuropathogenesis and
neuroprotective mechanisms underlying Huntington’s disease, Alzheimer’s disease
and cerebral ischemic stroke. Specifically, he utilizes multiple approaches,
including molecular biology, biochemistry, cell biology (including induced
pluripotent stem cells, iPSCs), and mouse models, to (1) understand why
neurodegeneration occurs in specific pathological conditions, (2) identify
targets that can be “druggable” for treating the neurodegenerative disorders,
and (3) develop therapeutic compounds that can be used for treating these
disorders.
Michael Watt, Ph.D.
Associate Professor
Basic Biomedical Sciences
Sanford School of Medicine
University of South Dakota
Talk Title: "Consequences of adolescent social stress on prefrontal cortex dopamine function and related behaviors"
Dr. Watt obtained his Ph.D. in
Behavioral Endocrinology at Macquarie University in 2002 and is currently an
Associate Professor in the Sanford School of Medicine. He has utilized a
variety of invertebrate and vertebrate models to examine how differences in
individual social responses relate to alterations in limbic monoaminergic
activity and endocrine stress responses, and how this can be further
differentiated by prior social experience. Currently, his NSF and NIH funded
research uses a rat model to investigate mechanism underlying how social stress
in adolescence negatively affects prefrontal cortex dopamine function and
related behavior, and how this may be restored in adulthood.
